|
| BREAST |
| MMC
| Partial Breast Radiation Therapy Delivered Via High Dose
Rate Brachytherapy and Mammosite™ Device |
| MMC
| A Pilot Study of Limited Field Intensity Modulated Radiotherapy
in the Management of Early Stage Breast Cancer |
| RTOG
9804 | Phase III Trial of Tamoxifen Alone vs. Tamoxifen Plus
RT for Good Risk Duct Carcinoma In-Situ (DCIS) of the Female Breast Patient
|
| NSABP-31 | A Randomized
Trial Comparing The Safety and Efficacy of Adriamycin and Cytoxan Followed by
Taxol (AC-T) To That of Adriamycin and Cytoxan Followed by Taxol Plus Herceptin
(AC-T+H) in Node + Breast Cancer Patients Who Have Tumors That Over express HER2
|
| NSABP B35 | A Clinical
Trial Comparing Anastrozole with Tamoxifen in Postmenopausal Patients with DCIS
Undergoing Lumpectomy with radiation Therapy |
| NSABP
B36 | A Clinical Trial of Adjuvant Therapy Comparing Six
Cycles of 5-Fluorouracil, Epirubicin and Cyclophosphamide (FEC) to Four Cycles
of Adriamycin and Cyclophosphamide (AC), With or Without Celecoxib, in Patients
with Node-Negative Breast Cancer |
| NSABP-2
|
Study of Tamoxifen and Raloxifene (STAR) for the Prevention
of Breast Cancer |
John
Wayne Cancer Institute/MedImmune Amifostine as a Radioprotectant
for Breast Cancer Patients with Augmented or Reconstructed Breasts Undergoing
Radiation Therapy
|
University
of Iowa/Department of Defense Clinical Evaluation of Digital
Mammography
|
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LUNG |
| RTOG
0017 | A Phase I Study of Gemcitabine, Carboplatin or Gemcitabine,
Paclitaxel, and Radiation Therapy Followed by Adjuvant Chemotherapy for Patients
with Favorable Prognosis Inoperable Stage IIIA/B Non-Small Cell Lung Cancer (NSCLC) |
| RTOG
0123 | A Phase II Randomized Trial with Captopril in patients
who have received Radiation Therapy +/- Chemotherapy For Stage II-IIIB NSCLC,
Stage I Central NSCLC, or Limited Stage Small cell lung cancer. |
| RTOG
0212 | A Phase I/II Randomized Trial of Two doses (PHASE III-Standard
VS. High) and Two dose high schedule (PHASE II-Once VS. Twice Daily) for delivering
prophylactic cranial irradiation for patients with Limited Disease Small Cell
Lung Cancer |
| RTOG 0213 | A
Phase I/II Trial of a Cox-2 Inhibitor, Celebrex™ with Limited Field Radiation
for Intermediate Prognosis Patients with Locally Advanced Non-Small Cell Lung
Cancer, with Analysis of Prognostic Factors |
| RTOG
0214 | A Phase III Comparison of Prophylactic Cranial Irradiation
versus Observation in Patients with Locally Advanced Non-Small Cell Lung cancer
|
| RTOG 0241 | Phase
I Study of Irinotecan and Cisplatin combination with twice daily thoracic radiotherapy
(45 Gy) or once daily thoracic radiotherapy (70 Gy) for patients with Limited
Stage Small Cell Lung Cancer |
| MedImmune | Open
Label, Multicenter trial of Amifostine in the Prevention of radiation Induced
Esophagitis and Pneumonitis in patients with Measurable, Non-resectable Non Small
Cell Lung Cancer |
| CINJOG | Phase
II Study of Weekly Docetaxel Together With Weekly Cisplatin in Chemotherapy Naïve
Patients With Stage IV or Select Stage IIIB (Malignant Effusion) Non-Small Cell
Lung Cancer |
| GI |
| CINJ | Phase
II Study of Gleevec (Imatinib Mesylate, formerly known as ST1571) in patients
with metastatic unresectable pancreatic cancer |
| RTOG
E-0113 | Non-Operative Therapy of Local-Regional Carcinoma
of the Esophagus: A Randomized Phase II Study of Two Paclitaxel-Based Chemo radiotherapy
Regimens |
| RTOG S-0132 | A
Phase II Trial of Neo Adjuvant STI-571 (Gleevec) for Primary and Recurrent Operable
Malignant GIST Expressing KIT Receptor Tyrosine Kinase (CD117) |
| RTOG
0246 | A Phase II Study of a paclitaxel-based chemoradiotherapy
regimen with selective surgical salvage for respectable loco regionally advanced
carcinoma of the esophagus |
| RTOG
0315 | A Randomized, Double Blind, Placebo-Controlled Phase
III Study to Determine the Efficacy of Sandostatin Laro® Depot (OCTREOTIDE
ACETATE) in Preventing or Reducing the Severity of Chemoradiation-Induced Diarrhea
in Patients with Anal or Rectal Cancer |
| RTOG
9811 | A Phase III Randomized Study of 5-FU, Mitomycin-C,
and RT versus 5-FU, CDDP and RT in Carcinoma of the Anal Canal |
| MMC | Preoperative
Chemoradiation with Celebrex for Rectal Cancer |
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| BLADDER |
| CINJ
5976 | A Phase I/II Trial of Gemcitabine, Carboplatin and
Taxol Combination Therapy in Patients with Advanced Malignancy and Locally Advanced
Unresectable Metastatic Urothelial Cancer |
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| GYNECOLOGY |
| RTOG
0116 |
A Two Part
Phase I/II Study of Extended Field External Irradiation and Intracavitary Brachytherapy
combined with Chemotherapy (weekly Cisplatin-Arm 1) and Amifostine (weekly Cisplatin
and Amifostine - Arm 2) in carcinoma of the cervix with positive para-aortic of
high common iliac lymph nodes. |
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| HEAD
AND NECK |
| McNeil | The
ARISE study
A double blind, randomized, vehicle controlled study comparing
the safety and efficacy of Benzydamine Hydrochloride 0.15% Oral Rinse |
| RTOG 0022 | Conformal and
Intensity Modulated Irradiation for Oropharyngeal Cancer |
| RTOG 0129 | A Phase III
Trail of Concurrent Radiation and Chemotherapy for Advanced Head and Neck Carcinomas |
| RTOG 0225 | A Phase II Study
of Intensity Modulated Radiation Therapy (IMRT) + 1 - Chemotherapy for Nasopharyngeal
Cancer |
| RTOG 0324 |
A Phase II Study of Cetuximab (C225) in Combination with Chemoradiation in Patients
with Stage IIIA/B Non-Small Cell Lung cancer |
| NCI
4551 | A Phase I Study of ZD 1839 (Iressa) in Combination
with Radiation and Chemotherapy in Locally Advanced Squamous Cell carcinoma of
the Head and Neck Patients |
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| PROSTATE |
| MMC | A Prospective Evaluation
of Feasibility and Validation of Intensity Modulated Radiation Therapy for Prostate
Cancer at High Dose Levels |
| MMC
| Phase I Study to Evaluate the use of Brachytherapy for
Salvage of recurrent Prostate Cancer Following Definitive Treatment with External
Beam Radiotherapy |
RTOG
9902 | A Phase II Protocol of Androgen
Suppression (AS) and RT as an Rx Followed by Chemo with Paclitaxel, Estramustine,
and Etoposide for Localized, High Risk, Prostate Cancer |
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| BRAIN |
| RTOG 9813 | A Phase I/III
Randomized Study of Radiation Therapy and Temozolomide Versus Radiation Therapy
and BCNU Versus Radiation Therapy and Temozolomide and BCNU for Anaplastic Astrocytoma |
| RTOG 0131 | A Phase II Trial
of Pre Irradiation and Concurrent Temozolomide in Patients with Newly Diagnosed
Anaplastic Oligodendrogliomas and Mixed Anaplastic Oligoastrocytomas |
| RTOG 0118 | A Phase III
Study of Conventional Radiation Therapy Plus Thalidomide versus Conventional Radiation
therapy for Multiple Brain Metastases |
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| OTHER: |
| MMC | Study of Stereotactic
Body Radiotherapy for Recurrent or Metastatic Lesions to the Lung, Liver, Spine
and Viscera |
| NJCOC |
Elderly and Clinical Radiation Trials |
PROTOCOL
CLOSURES:
The following trials are closed to accrual |
| NSABP-30
| A Three Arm Randomized Trial to Compare Adjuvant Adriamycin
Followed by Taxotere (AC-T); Adriamycin and Taxotere (AT); and Adriamycin, Taxotere,
and Cyclophosphamide (ATC) in Breast Cancer Patients with Positive Axillary Lymph
Nodes |
| RTOG G-0114 |
A Randomized Phase II Comparison of Two Cisplatin-Paclitaxel Containing Chemoradiation
Regimens in Resected Gastric Cancers |
| RTOG
9904 | A Phase II Trial of Preoperative Chemotherapy and
Chemo radiotherapy for Potentially Resectable Adenocarcinoma of the Stomach |
| RTOG 9910 | A Phase III
Trial to Evaluate the Duration of Neoadjuvant Total Androgen Suppression (TAS)
and RT in Intermediate Risk Prostate Cancer |
| RTOG
P 0011 | Phase III Randomized Study of Adjuvant Therapy
for High Risk pT2-3 N0 Prostate Cancer |
| CINJ |
Phase II Trial of Transdermal Estradiol in the Treatment of Hormone Refractory
Prostate Cancer |
| RTOG 0211 |
A Phase I/II Study of an Oral Epidermal Growth Factor Receptor Tyrosine Kinase
Inhibitor, ZD1839 (Iressa) with Radiation Therapy in Glioblastoma Multiforme |
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| LINKS: |
| NSABP | National Surgical
Adjuvant Breast and Bowel Project- NIH sponsored Research
www.nsabp.pitt.edu |
| RTOG | Radiation Therapy
Oncology Group- NIH sponsored Research
www.rtog.org |
| CINJOG | Cancer Institute
of New Jersey Oncology Group- NIH Sponsored Research
www.cinj.org |
| NJSCOC | New
Jersey State Commission on Cancer |
Copyright
© 2004 Monmouth Medical Center |
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